The idea of prosthetics is a tool. Most people's cell phones are prosthetics. If you leave your cell phone at home, you feel impacted by not having it. It's an important part of your daily function and what you can do in a day.
The nucleic acids have considerable biological importance because of their role in cell growth and in the transmission of hereditary characters.
My main efforts focussed on trying to identify the rate controlling steps during the cell cycle. Crucial for this analysis were wee mutants that were advanced prematurely through the cell cycle and so divided at a reduced cell size.
I have the utmost respect for synthesizers - Soft Cell, early Depeche Mode. But that's become a cliche for the '80s.
