Medicine is a very tough thing. I mean, everyone is going to die. Sooner or later. That's a tough thing to face.
You know, as a woman, it is tough to get to the top - like to get to that respected level in this industry - in any industry, I think.
I found acting tough; it takes a lot out of you if you have no technique.
It is always tough to win every booth right across the electorate because there are different issues in different parts of the electorate.
If one artist sells five million albums, the tendency is for other artists to say, 'Maybe I should do a little of that, too.' That can be tough to resist.
Voting has not been tough for me, for the most part, because there's guideposts about what will bring about the greatest amount of happiness for the greatest amount of people.
Women are usually only interesting to studio executives when they are fecund, between the ages of 15 and 30. I decided to get through the really tough patch, around 50, by just cutting my price and playing ten years older. I didn't want to have to wait until I was an old lady to play one.
Commanders-in-chief make really tough decisions.
People work for a living. They got families to raise. Their lives are tough.
I went from absolutely nothing to a lot of people judging me overnight, and it was really tough for me.
Predicting the market is always tough.
As a comedian, I'm forced to have a tough skin. Until people laugh, they are detractors. You walk into a new audience where nobody knows you, they go: 'Make us laugh. Show us what you're made of. Prove why we should be listening to you.'