I would be going until I went over the bounds of reality and was then caught up in a profound wish to be dead without having to go through the shaming defeat of suicide.
What a profound significance small things assume when the woman we love conceals them from us.
Sometimes a concept is baffling not because it is profound but because it is wrong.
I came away from the forums with a profound concern about the highly addictive and destructive nature of methamphetamine. Families are torn apart, lives are destroyed and treatment is difficult to get.
The implications of Americans devoting their lives to fast food are more profound than the fact that our kids aren't eating well. There are real repercussions that we need to know about and think about.
It is a profound and necessary truth that the deep things in science are not found because they are useful; they were found because it was possible to find them.
My dog and two cats are such a vital part of my life. To say that I am their owner doesn't reflect at all the profound bond and responsibility that I have towards them.
The American psyche has not recovered, and likely will not ever fully recover, from the profound and relentless incompetence of George W. Bush's disastrous, multitrillion-dollar war.
Although I was not aware of it at the time, the experience of growing up during the Great Depression was to have a profound impact on my intellectual and professional career.
My eyebrows make a more profound impact on other people than they do on me. I just let 'em grow.
Had I not stepped into the saddle in the first place, entire cultures, histories, and most importantly, profound connections with people and animals whom I now counted as my friends would have otherwise passed by, invisible.
It was a very profound experience, getting in touch with that part of us, in all of us human beings, that is committed beyond yourself to the point of giving everything you have, including your life, for other people, for your fellow man.
Living in France while the Falklands War was going on, I felt a profound sense of shame and betrayal, just as I did by the war in Iraq. People have asked why I don't talk about that directly in my plays. Well, politics needs to be articulated in many different ways.
He has a profound respect for old age. Especially when it's bottled.
Look, I worked with American Republican presidents and Democratic presidents, all of them, and each of them has shown a deep and profound friendship to Israel, you know? I can't remember anybody who was in that sense negative as far as Israel is concerned.
I've come to realize that an unencumbered U.S. senator is a profound threat to the whole system. It's somebody that they can't put in a box and say, 'Oh, well, we know how this guy is going to vote.'
I do believe very strongly that all of us and all of the other things in the context of our planet with Mother Nature, all of these things absolutely have a profound effect.
The possibility that members of the Trump team coordinated and colluded with agents of the Kremlin on Russia's interference in our elections is a profound and disturbing one, but it is pivotal that we approach this issue with the seriousness it deserves.
Your meditations may be as profound, as exalted, as devout as you like; you may practise every pious exercise you can manage, but all this is as nothing in comparison with the Blessed Sacrament. What we do may be godly, but this sacrament is God Himself!
The cosmical importance of this conclusion is profound and the possibilities it opens for the future very remarkable, greater in fact than any suggested before by science in the whole history of the human race.
When I was about to turn 50, I went into a kind of personal revision and observed my own priorities and what led those priorities in my life. And many things that, in a way, were profound.
A transfer of money should never be involved in this profound situation. Although illness is profound, too, but medicine's a business today. It's a business.
While overeating would be seen by some as an indulgence of self, it is in fact a profound rejection of self. It is a moment of self-betrayal and self-punishment, and anything but a commitment to one's own well-being.
The simplest questions are the most profound. Where were you born? Where is your home? Where are you going? What are you doing? Think about these once in a while and watch your answers change.
Genius might be the ability to say a profound thing in a simple way.
We sing a little song before we eat, a little blessing before we eat, and it's really - we're thanking the Lord and the Earth for the food that we eat, and it really brings you together in a profound kind of way.
Obviously, there has to be a profound change in direction. Otherwise, interest on the national debt will start eating up virtually every penny that we have.
A lot of people like the idea of eternal love and eternal romance. The notion of love that is more profound and deeper because it is eternal is very powerful.
Words will not be able to ever express how sorry I am for this, and I have profound regret and sorrow for the multitude of mistakes and harm I have caused.
It is not that the French are not profound, but they all express themselves so well that we are led to take their geese for swans.
I think my Buddhist practice has a profound influence on my life and encompasses my creative projects.
A profound political question is suddenly on the table: Must the country continue to give precedence to private financial gain and market determinism over human lives and broad public values?
In the strange heat all litigation brings to bear on things, the very process of litigation fosters the most profound misunderstandings in the world.
Indeed, the history of 20th century physics was in large measure about how to avoid the infinities that crop up in particle theory and cosmology. The idea of point particles is convenient but leads to profound, puzzling troubles.
The most striking development of the great depression of 1929 is a profound skepticism of the future of contemporary society among large sections of the American people.
Global climate change has a profound impact on the survival and development of mankind. It is a major challenge facing all countries.
