Frank Macfarlane Burnet - Human insulin differs from other mammalian types by having a different C-t...

Frank Macfarlane Burnet Zitate

Human insulin differs from other mammalian types by having a different C-terminal amino acid on the B chain. The immunological difference between beef insulin and human insulin, which is presumably responsible for the antigenicity of the former in some human beings, is thus limited to very a small portion of the whole molecule.

Frank Macfarlane Burnet

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Deutsche Übersetzung

Humaninsulin unterscheidet sich von anderen Säugetiertypen dadurch, dass es eine andere C-terminale Aminosäure an der B-Kette aufweist. Der immunologische Unterschied zwischen Rinderinsulin und Humaninsulin, der vermutlich bei einigen Menschen für die Antigenität des ersteren verantwortlich ist, ist daher auf einen sehr kleinen Teil des gesamten Moleküls beschränkt.

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