Zitat des Tages von María Blasco Marhuenda:
A short telomere represents a persistent and non-repairable damage to the cells, which is able to prevent their division or regeneration.
We still don't know what evolutionary significance to attach to it, but it is at the very least interesting that a telomere gene is related to obesity.
We believe that such a significant increase in longevity is due to the protective effect against cancer produced by caloric restriction - incidences fall by 40 percent if we compare them with the mice that produce more telomerase and have a normal diet - and, added to the presence of longer telomeres, this makes the mice live longer and better.
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.